Biochemistry

John C. Wilkinson

Chris Williamson — Mon, 09 Nov 2009 18:45:13 GMT

John C. WilkinsonMy laboratory is examining the role of the intrinsic cellular suicide program known as apoptosis in the pathogenesis of human disease. We are currently focused on the study of two factors, X linked inhibitor of apoptosis (XIAP) and

Yuh-Hwa Wang

Chris Williamson — Mon, 09 Nov 2009 18:39:46 GMT

Yuh Hwa WangOur research focus is to understand the structure and function of unusual DNA sequences in living cells and how these sequences lead to human diseases. Human chromosomal fragile sites have been correlated with the chromosomal deletions and gene

Alan J. Townsend

Chris Williamson — Mon, 09 Nov 2009 18:36:35 GMT

Alan J. TownsendExperimental Therapeutics and Drug Chemical Resistance The process of natural selection has resulted in the evolution of a diverse array of defensive mechanisms that organisms can utilize to survive in a toxic environment. These include changes in the

Alan Townsend - OTEO562

Chris Williamson — Tue, 10 Nov 2009 08:01:38 GMT

Alan Townsend - GSTP-1

Chris Williamson — Tue, 10 Nov 2009 08:01:38 GMT

Suzy Torti

Chris Williamson — Mon, 09 Nov 2009 18:26:34 GMT

Suzy TortiOur laboratory is interested in relationships between iron metabolism and tumor growth. This interest generates three current projects Natural and synthetic cancer chemopreventives and their relationship to iron chelation. Cancer angiogenesis and iron metabolism. Angiogenesis plays a key role

Michael J Thomas - apoA-I

Chris Williamson — Tue, 10 Nov 2009 08:01:37 GMT

Michael J. Thomas

Chris Williamson — Mon, 09 Nov 2009 18:15:49 GMT

Michael J. ThomasThe primary area of study is the identification of protein conformation using chemical cross linking coupled with mass spectrometric identification of the cross linked sites. In collaboration with Dr. Sorci Thomas we are presently working on the configuration

Peter B. Smith

Chris Williamson — Mon, 09 Nov 2009 18:10:30 GMT

Peter B. SmithExposure of living organisms to foreign chemicals (xenobiotics) often leads to physiologic disturbances culminating in cytotoxicity, mutation and cell transformation. The disturbance is frequently initiated when the xenobiotic is converted into reactive metabolites by enzyme systems native to

Pete Smith - P450

Chris Williamson — Tue, 10 Nov 2009 08:01:36 GMT

Susan Sergeant

Chris Williamson — Mon, 09 Nov 2009 18:05:31 GMT

Susan Sergeant“… no one with an unbiased mind can study any living creature, however humble, without being struck with enthusiasm at its marvelous structure and properties.” Charles Darwin, 1874 Cells inspire the same awe. Our research is focused on understanding

Lawrence L. Rudel - Dietary FC

Chris Williamson — Tue, 10 Nov 2009 08:01:24 GMT

Lawrence L. Rudel

Chris Williamson — Mon, 09 Nov 2009 14:42:09 GMT

Lawrence L. RudelResearch into the causes of premature coronary heart disease has been the focus of the work in the Rudel laboratory for over 30 years. Nonhuman primate models of diet induced atherosclerosis have been studied, and nutritional components of

Leslie B. Poole

Chris Williamson — Mon, 09 Nov 2009 18:48:58 GMT

Leslie B. Poole - Antioxidant enzymes, cysteine based peroxidases (peroxiredoxins), flavin containing disulfide reductases, cysteine sulfenic acids in protein function and cell signaling, alkyl hydroperoxide reductases

Leslie Poole - Biochemistry

Chris Williamson — Tue, 10 Nov 2009 08:01:19 GMT

Fred Perrino - TREX2

Chris Williamson — Tue, 10 Nov 2009 08:01:47 GMT

Fred Perrino - Trex1

Chris Williamson — Tue, 10 Nov 2009 08:01:47 GMT

Fred W. Perrino

Chris Williamson — Mon, 09 Nov 2009 14:11:20 GMT

Fred W. Perrino - Nucleases in replication, repair, and disassembly of the human genome 3’ DNA exonucleases During the multi step processes of DNA replication, repair, recombination, and apoptosis, DNA is remodeled by enzymes containing 3’ exonuclease activities. The major 3’ exonuclease

Derek Parsonage - Glycerol Uptake

Chris Williamson — Tue, 10 Nov 2009 08:01:46 GMT

Derek Parsonage

Chris Williamson — Mon, 09 Nov 2009 13:47:37 GMT

Derek ParsonageMy research focuses on several enzymes expressed by the Gram positive bacteria Enterococci. These enzymes include the flavoproteins NADH peroxidase, NADH oxidase and glycerophosphate oxidase. These have all been cloned, sequenced and overexpressed in E. coli. The enzymic mechanisms

Charles S. Morrow

Chris Williamson — Fri, 06 Nov 2009 20:55:59 GMT

Charles S. Morrow -

Linda C. McPhail

Chris Williamson — Wed, 04 Nov 2009 19:38:00 GMT

Focus on elucidation of cellular signal transduction mechanisms involved in the activation of NADPH oxidase, an enzyme responsible for the generation of toxic oxygen radicals in many cell types.

Linda McPhail - NADPH Oxidase

Chris Williamson — Thu, 05 Nov 2009 08:00:24 GMT

Douglas S. Lyles

Chris Williamson — Wed, 04 Nov 2009 19:25:59 GMT

Dr. Douglas S. Lyles' laboratory studies the structure, assembly, and pathogenesis of enveloped RNA viruses.

W. Todd Lowther

Chris Williamson — Wed, 04 Nov 2009 19:21:43 GMT

The overall focus of several ongoing projects in my laboratory is to understand the molecular basis for enzyme catalysis and substrate/inhibitor/ligand specificity.

Mark O. Lively

Chris Williamson — Wed, 04 Nov 2009 18:55:25 GMT

The primary focus of this laboratory is on the cellular roles and mechanisms of catalysis of novel proteolytic enzymes involved in the processing and secretion of proteins from eukaryotic cells.

David A. Horita

Chris Williamson — Wed, 04 Nov 2009 18:50:05 GMT

Research in my laboratory focuses on the structural biology underlying regulation of the generation of reactive oxygen species (ROS).

Thomas Hollis

Chris Williamson — Wed, 04 Nov 2009 18:43:29 GMT

Thomas HollisThe maintenance of DNA integrity is essential for normal cellular function and for the propagation of the genetic code to successive generations. A variety of endogenous cellular reagents and exogenous toxins are capable of reacting with and modifying DNA.

Tom Hollis - mTREXI-DNA

Chris Williamson — Thu, 05 Nov 2009 08:00:23 GMT

Roy R. Hantgan

Chris Williamson — Wed, 04 Nov 2009 18:46:24 GMT

Roy R. HantganCardiovascular disease is the leading cause of death in our society, and the major culprit is a blood clot formed by the unwarranted activation of the clotting cascade. While cardiologists can often restore normal blood flow through by

Roy Hantgan - integrin antagonists

Chris Williamson — Thu, 05 Nov 2009 08:00:23 GMT

Larry W. Daniel

Chris Williamson — Wed, 04 Nov 2009 18:35:23 GMT

Phospholipids are now known to be important molecules in the generation of second messengers during signal transduction in cellular responses to hormones and growth factors. My laboratory is studying the metabolic pathways responsible for forming lipid derived second

Al Claiborne

Chris Williamson — Mon, 09 Nov 2009 18:50:13 GMT

Gram-positive bacteria such as the streptococci present an intriguing system for investigating the structural, functional, and genetic aspects of oxygen metabolism.

Al Claiborne - Streptococcus pyogenes

Chris Williamson — Thu, 05 Nov 2009 08:00:22 GMT

YuNanmeng

Chris Williamson — Thu, 05 Nov 2009 08:00:17 GMT

AnSandy

Chris Williamson — Thu, 05 Nov 2009 08:00:16 GMT

Graduate Students

Chris Williamson — Tue, 10 Nov 2009 16:32:58 GMT

Graduate Students Audrey LenhausenE mail alenhaus@wfubmc.edu Jason SmedbergE mail jsmedber@wfubmc.edu

Shaban

Chris Williamson — Wed, 04 Nov 2009 08:00:43 GMT

Pryor

Chris Williamson — Wed, 04 Nov 2009 08:00:42 GMT

Cary

Chris Williamson — Wed, 04 Nov 2009 08:00:42 GMT

Burrow

Chris Williamson — Wed, 04 Nov 2009 08:00:41 GMT

Williams

Chris Williamson — Wed, 04 Nov 2009 08:00:39 GMT

Ritchie

Chris Williamson — Wed, 04 Nov 2009 08:00:39 GMT

Reidel

Chris Williamson — Wed, 04 Nov 2009 08:00:39 GMT

Huhn

Chris Williamson — Wed, 04 Nov 2009 08:00:38 GMT

Haynes

Chris Williamson — Wed, 04 Nov 2009 08:00:38 GMT

Fye

Chris Williamson — Wed, 04 Nov 2009 08:00:38 GMT

Manring

Chris Williamson — Wed, 04 Nov 2009 08:00:37 GMT

Orebaugh

Chris Williamson — Wed, 04 Nov 2009 08:00:37 GMT

Smedberg

Chris Williamson — Wed, 04 Nov 2009 08:00:36 GMT

Lenhausen

Chris Williamson — Wed, 04 Nov 2009 08:00:35 GMT

Rector

Chris Williamson — Wed, 04 Nov 2009 08:00:33 GMT

Rajani

Chris Williamson — Wed, 04 Nov 2009 08:00:33 GMT

Holland

Chris Williamson — Wed, 04 Nov 2009 08:00:32 GMT

Suzanna

Chris Williamson — Wed, 04 Nov 2009 08:00:32 GMT

QR - Biochemistry

Chris Williamson — Wed, 11 Nov 2009 15:04:22 GMT

BiochemistryBiochemistryPhone3367164689Fax3367167671E mailbiochemrecruit@wfubmc.eduApply to Graduate School

Peter Antinozzi - functional mapping

Chris Williamson — Tue, 03 Nov 2009 08:00:23 GMT

Peter A. Antinozzi

Star Lee — Mon, 09 Nov 2009 19:00:01 GMT

Peter A. Antinozzi - Functional genomics, Functional mapping, and High-throughput, high-content screening.

Donald W. Bowden

Chris Williamson — Fri, 06 Nov 2009 19:10:39 GMT

Research in our laboratory is focused on efforts to identify human genes that contribute to common diseases in our population.

Peter Antinozzi - High-throughput screening

Chris Williamson — Tue, 03 Nov 2009 08:00:20 GMT

Maryam Ahmed

Chris Williamson — Tue, 03 Nov 2009 19:17:40 GMT

Maryam Ahmed.

Determining the mechanisms by which viruses target and kill tumor cells is the central theme of my research.

Facilities

Chris Williamson — Wed, 04 Nov 2009 17:57:16 GMT

Major Instrumentation and Resources within Biochemistry and Wake Forest University School of Medicine.

Cancer

Ektron TestUser — Wed, 12 Aug 2009 19:05:28 GMT

The third principal research focus in the Department of Biochemistry involves programs devoted to the molecular, nutritional, and genetic bases for cancer and other common chronic human diseases.

Lipids

Ektron TestUser — Wed, 12 Aug 2009 18:36:14 GMT

One of the major research strengths in the Department of Biochemistry lies in the wealth of expertise regarding lipid-mediated signal transduction processes, lipid:protein interactions, and lipoprotein function and metabolism. This section describes the research programs of seven faculty members in the Department.

Proteins

Ektron TestUser — Fri, 14 Aug 2009 18:48:27 GMT

A rapidly-growing research strength within the Department of Biochemistry concerns structural, functional, and genetic studies of proteins and enzymes. With an emphasis on faculty recruitment over the last 2 years, the number of faculty members with research interests in this area has recently gone from eight to twelve X-ray crystallographers.

Research Programs

Ektron TestUser — Wed, 12 Aug 2009 18:19:35 GMT

The programs featured here are Proteins: Structure, Function and Genetics; Lipids Involved in Signal Transduction and Lipid: Protein Interactions; Cancer and the Molecular Basis of Disease.

Fellowships

Chris Williamson — Tue, 03 Nov 2009 18:06:50 GMT

We invite applications for postdoctoral training in the Department of Biochemistry. The Department features research and training in structural biology, molecular biology, genetics/genomics, and proteomics/metabolomics.

Faculty

Chris Williamson — Mon, 09 Nov 2009 18:46:18 GMT

The Biochemistry faculty and their research

Summer Research Projects for Undergraduates

Chris Williamson — Tue, 03 Nov 2009 18:10:04 GMT

Following is a listing of Summer Research Projects for Undergraduates by Faculty member.

Seminars

Chris Williamson — Wed, 11 Nov 2009 16:02:07 GMT

Department of Biochemistry student and faculty seminar schedule.

Guidelines for Graduate Students

Chris Williamson — Tue, 03 Nov 2009 18:08:31 GMT

Guidelines for Graduate Students in Biochemistry and Molecular BiologyGuidelines for Graduate StudentsPrerequisites All entering students are expected to have developed competence in fundamental areas of basic science. For all students, these minimal requirements include a two semester course in organic

Graduate Program

Chris Williamson — Thu, 05 Nov 2009 16:24:42 GMT

The Graduate Program at a GlanceGraduate Program The Wake Forest University School of Medicine Department of Biochemistry offers the Ph.D. degree in Biochemistry and Molecular Biology through the Graduate School of Wake Forest University, and is recruiting highly motivated and

About Biochemistry

Chris Williamson — Mon, 16 Nov 2009 14:48:56 GMT

Department of Biochemistry AffiliationsAffiliationsThe Department of Biochemistry Affiliations Wake Forest University School of Medicine Structural Biology Biochemistry and Molecular Biology Graduate School of Arts and Sciences Wake Forest University

Biochemistry

Ektron TestUser — Thu, 29 Oct 2009 15:25:15 GMT

The Department features research and training in 4 key technologies that form the core of modern biochemistry: Structural Biology; Molecular Biology; Genetics/Genomics; Proteomics/Metabolomics.

biochem_image

Internal Administrator — Thu, 09 Jul 2009 01:24:17 GMT