Tissue that is engineered in the lab not only has to look like the tissue it will replace -- it has to function like it as well. The organ bath is an experimental set-up that is used to test laboratory-engineered tissue. With organ bath experiments, scientists study how the tissue responds to chemical agents and/or electrical impulses to determine if the responses are normal.
The tissue is suspended in a temperature-controlled chamber and its contractile function is recorded on a computer. By comparing the contraction and relaxation responses of engineered tissue to normal tissue, we can assess the success of our experiments.
Watch the organ bath system being used to investigate the properties of engineered muscle tissue.
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