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Transporters as drug targets: discovery and development of NPC1L1 inhibitors. Betters JL, Yu L. Clin Pharmacol Ther. 2010 87(1) : 117-121

Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8. Tang W, Ma Y, Jia L, Ioannou YA, Davies JP, Yu L. J Lipid Res. 2009 50(2) : 293-300

Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol. Li Z, Park T-S, Li Y, Pan X, Iqbal J, Lu D, Tang W, Yu L, Goldberg IJ, Hussain MM, et al. Biochim Biophys Acta. 2009 1791(4) : 297-306

Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent. Temel RE, Brown JM, Ma Y, Tang W, Rudel LL, Ioannou YA, Davies JP, Yu L. J Lipid Res. 2009 50(5) : 915-923

Kinetic imaging of NPC1L1 and sterol trafficking between plasma membrane and recycling endosomes in hepatoma cells. Petersen NH, Faergeman NJ, Yu L, Wustner D. J Lipid Res. 2008 49(9) : 2023-2037

Serine palmitoylCoA transferase-deficient mice absorb less cholesterol [abstract]. Li Z, Park T-S, Li Y, Iqbal J, Tang W, Yu L, Hussain MM, Jiang X-C. Arterioscler Thromb Vasc Biol. 2008 28(6) : e-130

The structure and function of Niemann-Pick C1-like 1 protein. Yu L. Curr Opin Lipidol. 2008 19(3) : 263-269

Niemann-Pick C1-like 1 is required for an LXR agonist to raise plasma HDL cholesterol in mice. Tang W, Ma Y, Jia L, Ioannou YA, Davies JP, Yu L. Arterioscler Thromb Vasc Biol. 2008 28(3) : 448-454

CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells. Brown JM, Chung S, Das A, Shelness GS, Rudel LL, Yu L. J Lipid Res. 2007 48(10) : 2295-2305

Dual action of the ezetimibe target Niemann-Pick C1-Like 1 [editorial]. Yu LQ. Future Lipidol. 2007 2(4) : 379-382

Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe. Temel RE, Tang W, Ma Y, Rudel LL, Willingham MC, Ioannou YA, Davies JP, Nilsson L-M, Yu L. J Clin Invest. 2007 117(7) : 1968-1978

Intestinal cholesterol absorption is required for the LXR agonist to increase plasma HDL cholesterol in mice [abstract]. Tang WQ, Ma YY, Jia L, Yu LQ. Arterioscler Thromb Vasc Biol. 2007 27(6) : e-36

NPC1L1 (Niemann-Pick C1-like 1) mediates sterol-specific unidirectional transport of non-esterified cholesterol in McArdle-RH7777 hepatoma cells. Brown JM, Rudel LL, Yu L. Biochem J. 2007 406(2) : 273-283

Acyl-Coa:cholesterol acyltransferase 2 and ATP-binding cassette half transporters G5 and G8 differentially alter hepatic lipoprotein secretion and composition [abstract]. Alger HM, Parini P, Shah R, Yu L, Rudel LL. Arterioscler Thromb Vasc Biol. 2007 27(6) : e-57

Plasma cholesterol is hyperresponsive to statin in ABCG5/ABCG8 transgenic mice. Tang W, Ma Y, Yu L. Hepatology. 2006 44(5) : 1259-1266