Profile

Gregory S. Shelness, Ph.D.

Gregory S. Shelness, Ph.D.

Professor, Pathology - Lipid Sciences
Comprehensive Cancer Center
Contact Information
Office:
336-716-3282
Fax:
336-716-6279
E-mail: gshelnes@wfubmc.edu
Education & Training
  BASUNY-Purchase1979
  PhDSUNY-Stony Brook1984
FellowshipRockefeller University1989
Gregory S. Shelness, Ph.D.

Gregory S. Shelness, Ph.D.

Professor, Pathology - Lipid Sciences
Comprehensive Cancer Center
Contact Information
Office:
336-716-3282
Fax:
336-716-6279
E-mail: gshelnes@wfubmc.edu
Recent Publications
Mulya A, Seo J, Brown AL, Gebre AK, Boudyguina E, Shelness GS, Parks JS. Apolipoprotein M expression increases the size of nascent pre beta HDL formed by ATP binding cassette transporter A1. J Lipid Res. 2010; 51(3):514-524.


Chung S, Timmins JM, Duong M, Degirolamo C, Rong S, Sawyer JK, Singaraja RR, Rudel LL, Shelness GS, Parks JS, et al. Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism. J Biol Chem. 2010; 285(16):12197-209.


Chung S, Gebre AK, Seo J, Shelness GS, Parks JS. A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion. J Lipid Res. 2010; 51(4):729-742.


Cheng D, MacArthur PS, Rong S, Parks JS, Shelness GS. Alternative splicing attenuates transgenic expression directed by the apolipoprotein E promoter-enhancer based expression vector pLIV11. J Lipid Res. 2010; 51(4):849-855.


Seo J, Mulya A, Gebre AK, Tall A, Shelness GS, Parks JS. ApoM expression causes formation of larger nascent HDL particles and preferential cholesterol efflux from late endosomes by ABCA1 [abstract]. Arterioscler Thromb Vasc Biol. 2009; 29(7):e71.


Degirolamo C, Shelness GS, Rudel LL. LDL cholesteryl oleate as a predictor for atherosclerosis: evidence from human and animal studies on dietary fat. J Lipid Res. 2009; 50(Suppl):S434-S439.


MacArthur PS, Shelness GS. Mechanism of neutral lipid translocation across the endoplasmic reticulum membrane [abstract]. Arterioscler Thromb Vasc Biol. 2009; 29(7):e105.


Ledford AS, Cook VA [sic] [Cook VR], Shelness GS, Weinberg RB. Structural and dynamic interfacial properties of the lipoprotein initiating domain of apolipoprotein B. J Lipid Res. 2009; 50(1):108-115.


Chung S, Timmins JM, Duong M, Rong S, Sawyer JK, Maeda N, Rudel LL, Shelness GS, Parks JS. Targeted deletion of hepatocyte ABCA1 induces futile cycling of VLDL production and clearance in C57BL/6 mice [abstract]. Arterioscler Thromb Vasc Biol. 2009; 29(7):e36.


Blade AM, Hou L, Shelness GS. Biogenesis and posttranscriptional regulation of apolipoprotein [abstract]. Arterioscler Thromb Vasc Biol. 2008; 28(6):e-59.


Chung S, Timmins J, Duong M, Seo J, Gebre A, Boudyguina E, Shah R, Sawyer J, Rudel L, Shelness G, Parks JS, et al. Hepatic-specific deletion of ABCA1 promotes PI3 kinase-dependent VLDL maturation: a novel role for ABCA1 in the regulation of VLDL triglyceride assembly [abstract]. Arterioscler Thromb Vasc Biol. 2008; 28(6):e-93-e-94.


Chung S, Timmins JM, Duong M, Seo J, Gebre A, Boudyguina E, Rudel LL, Shelness G, Shah R, Sawyer J, Parks JS, et al. A novel role for Abca1-generated large nascent HDL in the regulation of VLDL triglyceride secretion [abstract]. Circulation. 2008; 118(18 Suppl 2):S558.


Brown JM, Chung S, Das A, Shelness GS, Rudel LL, Yu L. CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells. J Lipid Res. 2007; 48(10):2295-2305.


Brown JM, Shelness GS, Rudel LL. Monounsaturated fatty acids and atherosclerosis: opposing views from epidemiology and experimental animal models. Curr Atheroscler Rep. 2007; 9(6):494-500.


Temel RE, Hou L, Rudel LL, Shelness GS. ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins. J Lipid Res. 2007; 48(7):1618-1627.


Mohler PJ, Zhu M-Y, Blade AM, Ham A-JL, Shelness GS, Swift LL. Identification of a novel isoform of microsomal triglyceride transfer protein. J Biol Chem. 2007; 282(37):26981-88.


Krugner-Higby L, Shelness GS, Holler A. Heritable, diet-induced hyperlipidemia in California mice (Peromyscus californicus) is due to increased hepatic secretion of very low density lipoprotein triacylglycerol. Comp Med. 2006; 56(6):468-475.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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Last Updated 5/13/2010
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