Profile

Douglas S.  Lyles, Ph.D.

Douglas S. Lyles, Ph.D.

Program Director, Comprehensive Cancer Center
Professor, Biochemistry
Contact Information
Office:
336-716-4237
Education & Training
  BAUniversity of Pennsylvania1972
  PhDUniversity of Mississippi School of Medicine1975
FellowshipRockefeller University1978
Memberships
American Society of Biochem & Molecular Biology
American Society of Microbiology
American Society of Virology
Douglas S.  Lyles, Ph.D.

Douglas S. Lyles, Ph.D.

Program Director, Comprehensive Cancer Center
Professor, Biochemistry
Contact Information
Office:
336-716-4237
Research Interests
basic mechanisms , infectious diseases , molecular biology/molecular me , reproductive system , animals, whole , animals, cells/membranes/tissu , cell growth, differentiation,d , cancer/oncogenesis , human, cells only , genetics/genome , microorganisms
Recent Publications


Kneller ELP, Connor JH, Lyles DS. hnRNPs relocalize to the cytoplasm following infection with vesicular stomatitis virus. J Virol. 2009; 83(2):770-780.


Agnihothram SS, Dancho B, Grant KW, Grimes ML, Lyles DS, Nunberg JH. Assembly of arenavirus envelope glycoprotein GPC in detergent-soluble membrane microdomains. J Virol. 2009; 83(19):9890-9900.






Dancho B, McKenzie MO, Connor JH, Lyles DS. Vesicular stomatitis virus matrix protein mutations that affect association with host membranes and viral nucleocapsids. J Biol Chem. 2009; 284(7):4500-4509.


Whitlow ZW, Connor JH, Lyles DS. New mRNAs are preferentially translated during vesicular stomatitis virus infection. J Virol. 2008; 82(5):2286-2294.






Ahmed M, Marino TR, Puckett S, Kock ND, Lyles DS. Immune response in the absence of neurovirulence in mice infected with m protein mutant vesicular stomatitis virus. J Virol. 2008; 82(18):9273-9277.


Lyles DS, Rupprecht CE. Rhabdoviridae. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Straus SE, Martin MA, Roizman B, eds. Fields virology. 5th ed. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins; 2007: 1363-1408.


Connor JH, McKenzie MO, Parks GD, Lyles DS. Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses. Virology. 2007; 362(1):109-119.






All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Last Updated 5/27/2010
Loading...
Quick Reference
Important Numbers
Media Inquiries 
336-716-4587
Patient Information 
336-713-0000
To Arrange Satellite Interviews 
336-716-4434
Locate Faculty

e.g., "allergy," "diabetes"

Loading...

Disclaimer: The information on this Web site is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.