What we are studying
The purpose of this study is to find out if the drugs elesclomol sodium and paclitaxel will work in treating your type of cancer and to find out what side effects are caused by treatment with this drug combination.
Paclitaxel is a drug which has shown effectiveness in treating ovarian, uterine and cervical cancer. Elesclomol sodium is an investigational drug that is thought to help make cancer cells more responsive to paclitaxel. In a small comparative trial in advanced melanoma (skin cancer), the combination of paclitaxel and elesclomol was more effective than paclitaxel alone in shrinking cancerous tumors and slowing cancer growth and progression. However, in a conflicting larger study in advanced melanoma, there were more deaths in the paclitaxel-elesclomol arm than the paclitaxel alone arm (80 vs. 53).