What we are studying
The purpose of this study is to compare the effects, good and/or bad, of abiraterone, prednisone,and enzalutamide with enzalutamide alone on you and your prostate cancer to find out which is better. In this study, you will get either the combination of abiraterone, prednisone, and enzalutamide or enzalutamide alone. Abiraterone and enzalutamide are both hormonal agents approved by the Food and Drug Administration for patients with castration-resistant metastatic disease. Each drug works in a different way to block hormones.